Publications


  1. Kinney, J.P. and Darby, J.K., 1967. Radiation hazards and congenital malformations, National Foundation Merit Award Series.

  2. Darby, J.K., 1968. Neuropsychiatric aspects of Addison’s Disease, University of Utah Annals of Neurology.

  3. Darby, J.K., 1976 Neuropathologic aspects of psychosis in children, Journal of Autism and Childhood Schizophrenia, 6:339-352

  4. Darby, J.K. and Hollien, H., 1977. Vocal and speech patterns of depressive patients, Folia Phoniatrica, 29:279-291.

  5. Darby, J.K. and Sherk, A., 1979. Speech studies in psychiatric populations, In Harry Hollien and Patricia Hollien (Eds.), Current Issues in the Phonetic Sciences, Vol. 9 (Part II), Amsterdam, John Benjamins B.V., 599-608.

  6. Holien, H. and Darby, J.K., 1979. Acoustic comparisons of psychotic and nonpsychotic voices. In Harry Hollien and Patricia Hollien (Eds.), Current Issues in the Phonetic Sciences, Vol. 9 (Part II), Amsterdam, John Benjamins B.V., 609-614.

  7. Darby, J.K. l982. Advances in schizophrenia research; neuropathologic findings, The Behavioral and Brain Sciences, 5:598-599.

  8. Darby, J.K.; Simmons, N., and Berger, P.A. 1984. Speech and Voice Parameters of Depression: A pilot study, Journal of Communication Disorders, 17: 75-85.

  9. Darby, J.K., Feder, J., Selby, M., Riccardi, V., Ferrell, R., Siao, D., Goslin, K., Rutter, W., Shooter, E. M., and Cavalli-Sforza, L.L., 1985 Discordant sibship analysis between B-NGF and disseminated neurofibromatosis, Am., Jour. Hum. Gen., 37:52-59.

  10. Feder, J., Gurling H. M.D., Darby, J.K. and Cavalli-Sforza, L.L., 1985. DNA restriction fragment analysis of the proopiomelanocortin gene in schizophrenia and bipolar disorders, Am., Jour. Hum. Gen., 37:286-294.

  11. Darby, J.K., Kidd, J.R., Pakstis, A.J., Sparkes, R.S., Cann, H.M., Ferrell, R.E., Gerhard, D.G., Riccardi, V., Egeland, J.A., Shooter E.M., Cavalli-Sforza, L.L., and Kidd, K.K., 1985. Linkage relationships of the gene for the B subunit of nerve growth factor (NGFB) with other chromosome 1 marker loci. Jour. Of Cytogenetics and Cell Genetics, 39:158-160.

  12. Darby, J.K., Kidd, J.R., Feder, J., Riccardi, V., Ferrell, R.E., Shooter E.M., Kidd, K.K., and Cavalli-Sforza, L.L., 1985. Linkage analysis between disseminated neurofibromatosis and chromosome 1 markers. (Abs.) Eighth International Human Gene Mapping Workshop. Helsinki, Finland. Karger, 611.

  13. Darby, J.K., Goslin, K., Riccardi, V., Huson, S., Ferrell, R., Kidd, J.R., Seizinger, B., Ferrier, J., Shooter E.M., and Cavalli-Sforza, L.L., 1986. Linkage analysis between NGFB and other chromosome 1p markers and disseminated neurofibromatosis. In A.E. Rubenstein, R.P. Bunge, and D.E. Housman (Eds.), Neurofibromatosis. New York Acad. Sciences, 486:311-326.

  14. Kidd, K.K., Kidd, J.R., Castiglione, C., Genel, M., Darby, J.K., Cavalli-Sforza, L.L., and Gusella, J.F., 1986. Linkage analyses of multiple endocrine neoplasia, type 2A (MEN-2A) with 20 DNA polymorphisms: 5% of the genome excluded. Human Heredity, 36:243-249.

  15. Darby, J.K., Johnsen, J., Nakashima, P., Willems, P., O’Brien, J.S., Fowler, M.L., Shows, T.B., Shooter E.M., and Cavalli-Sforza, L.L., 1986. Pvu II RFLP at the human chromosome 1 alpha-L-fucosidase gene locus. Nucleic Acids Research, 14:9543.

  16. Gebicke-Haerter, P., Darby, J.K., Shooter E.M., Riccardi, V.M., Weisgraber, K., Boyles, J., and Mahley, R., 1987. Apolipoprotein E expression in neurofibrosarcoma and schwannoma cell cultures from two individuals with neurofibromatosis. Exp. Neurol., 95:323-335.

  17. Ferrell, R.E., Buetow, K.H., Darby, J.K., Eichner, J.E., Murray, J.C., Smith, R., Waziri, M., Huson, S., and Riccardi, V.M., 1987. Von Recklinghausen neuro-fibromatosis: A linkage study of candidate and random marker genes. Jour. of Med. Genetics, 24:522-524.

  18. O’Brien, J.S., Willems, P.J., Fukushima, H., de Wet, J.R., Darby, J.K., DiCioccio, R.A., Fowler, M.L., and Shows, T.B., 1987. Molecular biology of the alpha-L-fucosidase gene and fucosidosis. Enzyme, 38:45-53.

  19. O’Brien, J.S., Willems, P.J., Darby, J.K., and DiCioccio, R.A. 1987. A structural alteration of the FUCA 1 gene in fucosidosis. Abstract. Am. Jour. Hum. Gen., 41:A231.

  20. Tam, A.W., Darby, J.K., and Riccardi, V.M., 1988. Expression of selected growth factors and oncogenes in neurofibrosarcoma complicating von Recklinghausen disease. Neurofibromatosis, 1:69-84.

  21. Darby, J.K., Willems, P.J., Nakashima, P., Henke, J., Ferrell, R.E., Johnsen, J., Wijsman, E. M., Gerhard, D., Dracopoli, N.C., Housman, D., Fowler, M.L., Shows, T.B., O’Brien, J.S., and Cavalli-Sforza, L.L., 1988. Restriction and analysis and linkage of the structural alpha-L-fucosidase gene in fucosidosis. Am. Jour. Hum. Gen., 43:749-755.

  22. Willems, P.J., Darby, J.K., DiCioccio, R.A., Nakashima, P., Eng, C., Kretz, K.A., Cavalli-Sforza, L.L., Shooter E.M., and O’Brien, J.S., 1988. Identification of a mutation in the structural alpha-L-fucosidase gene in fucosidosis. Am. Jour. Hum. Gen., 43:756-763.

  23. Willems, P.J., Garcia, C., DeSmedt, M.C.H., Martin-Jimenez, R., Darby, J.K., and O’Brien, J.S., 1988. Intrafamilial variability in fucosidosis. Clinical Genetics, 34:7-14.

  24. DiCioccio, R.A., Darby, J.K., O’Brien, J.S., and Willems, P.J., August 1988. Alpha-L-fucosidase in fucosidosis. Abstract. The Protein Society.

  25. DiCioccio, R.A., Darby, J.K., O’Brien, J.S., and Willems, P.J., 1988. Alpha-L-fucosidase in fucosidosis. Abstract. Annual meeting of the Society for Complex Carbohydrates.

  26. Stephens, K., Green, P., Riccardi, V.M., Ng., S., Rising, M., Barker, D., Darby, J.K., Falls, K.M., Collins, F.S., Willard, H.F., and Donis-Keller, H., 1989. Genetic analysis of eight loci tightly linked to Neurofibromatosis 1. Am. Jour. Hum. Gen., 44:13-19.

  27. Kretz, K.A., Darby, J.K., Willems, P.J., and O’Brien, J.S., 1989. Characterization of the Eco R1 mutation in fucosidosis patients: A stop codon in the open reading frame. Jour of Mol. Neurosciece, 1:177-180.

  28. DiCioccio, R.A., Darby, J.K., and Willems, P.J., 1989. Abnormal expression of alpha-L-fucosidase in lymphoid cell lines of fucosidosis patients. Biochemical Genetics, 27:Nos. 5/6, 279-290.

  29. Welch, H.M., Darby, J.K., Pilz, A.J., Ko, C.M., and Carritt, B., 1989. Transposition, amplification and divergence in the origin of the DNF 15 loci. A polymorphic repetitive sequence family on chromosomes 1 and 3., Genomics, 5:423-430.

  30. Willems, P.J., Carritt, B., Coucke, P., Darby, J.K., Van der Auwera, B.J. and O’Brien, J.S., 1990. Bcl 1 RFLP in the fucosidase pseudogene on chromosome 2. Nucleic Acids Research, 18:5583.

  31. Willems, P.J., Gatti, R., Darby, J.K., Romeo, G., Durand, P., Dumon, J.E., and O’Brien, J.S., 1991. Fucosidosis revisited: A review study of 77 patients. Am. Jour. Med. Genet., 38:111-131.

  32. Darby, J.K., and Clark, L.D., 1992. Autism syndrome as a final common pathway of behavioral expression for many organic disorders. Amer. Jour. Psychiat., 149:1:146-147.

  33. Reyniers, E., Vits, L., DeBoulle, K., Van Roy, B., Van Velzen, D., de Graaff, E., Verkerk, A.J.M.H. Jorens, H.Z.J., Darby, J.K., Oostra, B., and Willems, P.J., 1993. The full mutation in the FMR-1 gene of male fragile X patients is absent in their sperm. Nature Genetics., 4:143-146.

  34. Van Camp, G., Vits, L., Coucke, P., Lyonnet, S., Schrander-Stumpel, C., Darby, J.K., Holden, J., Munnich, A., and Willems, P.J., 1993. A duplication in the L1CAM gene associated with X-linked hydrocephalus. Nature Genetics., 4:421-425.

  35. Dabiri, L.M., Pasta, D., Darby, J.K., and Mosbacher, D., 1994. Effectiveness of Vitamin E for treatment of long-term tardive dyskinesia. Amer. Jour. Psychiat., 151:6:925-926.

  36. Bakker, C.E., Verheij, C. Willemsen, R., van der Helm, R., Oerlemans, F., Vermey, M., Bygrave, A., Hoogeveen, A.T., Oostra, B.A., Reyniers, E., De Boulle, K., D’Hooge, R., Cras, P., van Velzen, D., Nagels, G., Martin, J.J., De Deyn, P.P., Darby, J.K., and Willems, P.J., 1994. Fmr knockout mice: A model to study fragile X mental retardation. Cell, 78:1-11.

  37. Coucke, P., Van Camp, G., Djoyodiharyo, B., Smith, S.D., Frants, R.R., Padberg, G.W., Darby, J.K., Huizing, E.H., Cremers, W.R.J., Kimberling, W.J., Oostra, B.A., Van de Heyning, P.H., and Willems, P.J., 1994. Linkage of autosomal dominant hearing loss to the short arm of chromosome 1 in two families., New England Jour. of Medicine, 331:7:425-431.

  38. Vits, L., DeBoulle, K., Reyniers, E., Handig, I., Darby, J.K., Oostra, B., and Willems, P.J., 1994. Apparent regression of the CGG repeat in FMR1 to an allele of normal size. Hum Genet., 94:523-526.

  39. Darby, J.K., Pasta, D., Dabiri, L., Clark, L., and Mosbacher, D., 1995. Haloperidol dose and blood level variability: Toxicity and interindividual and intraindividual variability in the nonresponder patient in the clinical practice setting. Jour. of Clin. Pyschopharm, 15:5:334-340.

  40. Darby, J.K., Pasta, D., Elfand, L., Dabiri, L., Clark, L., and Herbert, J., 1997. Risperidone dose and blood level variability: Accumulation effects and interindividual and intraindividual variability in the nonresponder patient in the clinical practice setting. Jour. of Clin. Pyschopharm, 17:6:478-484.

  41. Darby, J.K., Marynen, P., Johnsen, J., Shows, T.B., Cavalli-Sforza, L.L., and Shooter E.M., 1991. Hinc II RFLP on chromosome 2 at a unique human segment D2S. Nucleic Acids Research , (in prep

  42. Darby, J.K., Pasta, D., Wilson M., and Herbert, J., 2008. Long-Term Therapeutic Drug Monitoring of Risperidone and Olanzapine Identifies Altered Steady-State Pharmacokinetics, Clin. Drug Invest; 28 (9):553-564.

  43. Darby, J.K., Pasta, D., 2009. Darby, Pasta response to Charpiat, B, Body Mass Index and Weight Gain as Alternative or Complementary Hypothesis to Explain Olanzapine Concentration-Dose Ratio Accumulation. Clin Drug Invest 2009; 29(2):1


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